Possible causes:
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System date and time settings may be set incorrectly (Incorrect system clock is the most likely cause of Error: 80048820).
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softpub.dll may not be registered on the system.
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Incorrect proxy setting for Internet Explorer.
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Security settings may be blocking MSN Messenger.
Correct date and time settings:
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Double click on the clock in the taskbar and make sure that the computer's clock shows correct date and time
Register softpub.dll:
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Click Start, and then click Run.
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Type regsvr32 softpub.dll and then click OK.
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Restart MSN Messenger.
Remove any Internet Explorer proxy server settings:
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Launch Internet Explorer, and then click Tools > Internet Options.
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From the Internet Options dialog box, go to the Connections tab.
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Click LAN Settings…
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Un check the Use a proxy server for your LAN (These settings will not apply to dial-up or VPN connections) option
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Check the Automatically detect settings option
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Click OK and OK again to close Internet Options dialog box
Adjust the security settins of Internet Explorer:
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Launch Internet Explorer, and then click Tools > Internet Options.
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From the Internet Options dialog box, go to the Advanced tab.
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Scroll down to the Security Section.
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Clear the Check for server certificate revocation check box.
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Select the Use ssl 2.0 check box.
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Select the Use ssl 3.0 check box.
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Click OK to close Internet Options dialog box.
